ALNY · Alnylam Pharmaceuticals Inc
Price
Snapshot
50 fields · last close| Market Cap | $35.39B |
| P/E | 44.28 |
| Float | 133.4M |
| Beta | 0.34 |
| Volatility | 8.5% |
| Exchange | NASDAQ |
| Sector | Biotechnology |
| Cap tier | Large cap |
| Macro sensitivity | Low |
| Clavix score | 60 |
| Price | 263.50 |
| Change | −0.38% |
| Prev Close | 264.50 |
| Open | 265.94 |
| Day Low | 261.54 |
| Day High | 271.19 |
| Avg Vol | 2 |
| Avg $ Vol | $487.4M |
| 52W High | 495.55 |
| 52W Low | 197.81 |
| 52W Pos | 22.1% |
| From High | −46.83% |
| From Low | +33.21% |
| Max DD 1Y | −58.17% |
| Spread | 0.10% |
| Liquidity | Normal |
| SMA 20 | +11.99% |
| SMA 50 | +1.59% |
| SMA 200 | −18.20% |
| RSI (14) | 61.5 |
| Vol 30D | 110.4% |
| Vol 90D | 69.2% |
| 1Y Range | 198–496 |
| Daily bars | 887 |
| Perf Week | +11.81% |
| Perf Month | +15.64% |
| Perf Quarter | −12.89% |
| Perf Half Y | −17.48% |
| Perf Year | −40.88% |
| Perf YTD | −34.15% |
| Prev Day | −0.38% |
| Clavix | C |
| Debt / Eq | 3.42 |
| Curr Ratio | 2.76 |
| Int Cover | 4.6× |
| FCF Margin | 17.8% |
| Rev Growth | +66.9% |
| Profit | Profitable |
| Leverage | Very High |
| Sector rank | 25 / 35 |
Clavix risk grade
regraded every trading dayALNY grades C, 60 of 100. Steadiest on Macro Resilience (66), most exposed on Price Stability (36, fragile). 1 of the 4 weighted dimensions sit above the Biotechnology median. Ranks 25 of 35 in Biotechnology by Clavix score.
How rough the ride is
| ALNY | Biotechnology median | |
|---|---|---|
| Betavs the overall market · lower is steadier | 0.34 | 0.50 |
| Volatilityannualized | 8.5% | 13.2% |
| Max drawdown, past yearworst peak-to-trough fall | −58.2% | — |
| Typical daily movemedian absolute daily change | 1.40% | — |
| Days beyond ±3%of the last 252 sessions | 4719% | — |
How its days are spread
Daily returns over the last 252 sessions in 1% bins. Moves beyond ±6% land in the end bins.
52-week range
The bar runs from the lowest to the highest close of the last 252 sessions; the marker is the latest close.
Drawdown from the 1-year peak
Percent below the running high over the last 12 months. Zero is a fresh high.
Market sensitivity
| ALNY | Biotechnology median | |
|---|---|---|
| Beta to the markethow much it swings with the S&P 500 · lower is safer | 0.34 | 0.50 |
| Macro sensitivityrate, dollar and credit exposure bucket | Low | Low56% of 36 |
Where it sits on the macro scale
Low means rates, the dollar and credit spreads barely move it. Very High means they drive a large share of its swings. The counts are how many Biotechnology names sit in each bucket.
Where it ranks in its sector
Rank by Clavix score within the sector. Right is the top of the sector.
Price performance
| ALNY | |
|---|---|
| 1 week | +11.8% |
| 1 month | +15.6% |
| Year to date | −34.2% |
| 1 year | −40.9% |
Context for the rank, not itself a risk measure.
Recent coverage, scored
| ALNY | |
|---|---|
| Articles scoredthe most recent scored coverage, up to 30 | 30since 31 Jul |
| Average score0 most bearish, 100 most bullish | 45 |
| Bullish · bearisharticles above 60 · below 40 | 11 · 16 |
| Directionarticles whose tone is improving vs worsening | 11 ↑ 16 ↓ |
Where the article scores land
Each bar is a 10-point band of article scores. Below 40 reads bearish, above 60 bullish.
Balance sheet, against the sector
The shaded band is the middle half of the 36 Biotechnology names Clavix covers; the tick is the sector median.
Growth
| ALNY | |
|---|---|
| Revenue growthyear over year | +66.9% |
Financial Health is shown but does not count toward the grade. Why
0–100, higher is safer. The tick on each bar is the Biotechnology median. Click a dimension for the evidence behind it. Financial Health is shown but does not count toward the grade.
Against Biotechnology
36 companies| Metric | ALNY | Sector spread | Median |
|---|---|---|---|
| Beta | 0.34 | 0.50 | |
| Volatility | 8.5% | 13.2% | |
| P/E | 44.28 | 22.77 | |
| Debt / equity | 3.42 | 0.24 | |
| Current ratio | 2.76 | 3.73 | |
| FCF margin | 17.8% | 29.1% | |
| Interest coverage | 4.6× | -0.2× |
Recent news
most recent scored articles · the chip is the article’s score · click to openAlnylam presented new clinical data at the European Society of Cardiology Congress 2026 showing its drug AMVUTTRA (vutrisiran) works across different groups of patients with transthyretin amyloidosis (ATTR), a condition affecting the heart and other organs.
Ionis and AstraZeneca released full data from their late-stage CARDIO-TTRansform trial in cardiomyopathy, which had already been disclosed as missing its primary goal on July 9. Jefferies said the results are a neutral to negative readthrough for Alnylam.
The upcoming European Society of Cardiology Congress in Munich will be important for Alnylam, as the outlook for its two heart drugs for ATTR-CM (transthyretin amyloid cardiomyopathy, a condition where misfolded proteins build up in the heart) is uncertain after a competing drug's surprising trial failure.
Alnylam said it will present new clinical and real-world data on its heart drug AMVUTTRA (vutrisiran) and its experimental high blood pressure drug zilebesiran at the European Society of Cardiology Congress 2026 in Munich, following the release of detailed analyses from its HELIOS-B and KARDIA-3 studies.
Daiichi Life Insurance Co. Ltd. bought 5,873 shares of Alnylam Pharmaceuticals during the second quarter, according to the insurer's 13F filing with the SEC (the quarterly report large institutional investors must file listing their stock holdings). The article is truncated and provides no further details.
Nearest peers by size
Biotechnology| Ticker | Company | Grade | Mkt cap | P/E | Beta | |
|---|---|---|---|---|---|---|
| BIIB | Biogen Inc | B+ | $33.17B | 39.72 | 0.12 | Compare |
| RVMD | Revolution Medicines Inc | B- | $45.20B | — | 1.44 | Compare |
| INSM | Insmed Inc | C- | $27.66B | — | 0.82 | Compare |
| NTRA | Natera Inc | B- | $47.23B | — | 1.61 | Compare |
| INCY | Incyte Corp | B+ | $25.95B | 16.10 | 0.78 | Compare |
| UTHR | United Therapeutics Corp | A- | $21.89B | 16.03 | 0.51 | Compare |
| MRNA | Moderna Inc | F | $59.43B | — | 1.22 | Compare |
| ASND | Ascendis Pharma A/S | B+ | $16.91B | 19.37 | 0.38 | Compare |
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