NBIX · Neurocrine Biosciences Inc

NASDAQ Biotechnology Large Cap Clavix B+
141.35−0.65  (−0.46%)

Price

Snapshot

50 fields · last close
Market Cap$14.43B
P/E20.39
Float99.35M
Beta0.34
Volatility8.4%
ExchangeNASDAQ
SectorBiotechnology
Cap tierLarge cap
Macro sensitivityLow
Clavix score79.4
Price141.35
Change−0.46%
Prev Close142.00
Open138.51
Day Low137.90
Day High142.09
Avg Vol1
Avg $ Vol$178.6M
52W High186.12
52W Low122.14
52W Pos30.0%
From High−24.05%
From Low+15.73%
Max DD 1Y−27.15%
Spread0.10%
LiquidityNormal
SMA 20+0.88%
SMA 50−4.67%
SMA 200−3.86%
RSI (14)48.3
Vol 30D29.9%
Vol 90D33.1%
1Y Range122–186
Daily bars538
Perf Week+5.08%
Perf Month−1.36%
Perf Quarter−17.77%
Perf Half Y+9.05%
Perf Year+1.36%
Perf YTD+0.53%
Prev Day−0.46%
ClavixB+
Debt / Eq0.00
Curr Ratio3.39
Int Cover3.0×
FCF Margin26.2%
Rev Growth+21.4%
ProfitProfitable
LeverageLow
Sector rank6 / 35

Clavix risk grade

regraded every trading day
B+79.4/100

NBIX grades B+, 79.4 of 100. Steadiest on Macro Resilience (71), most exposed on Price Stability (62, mixed). 2 of the 4 weighted dimensions sit above the Biotechnology median. Ranks 6 of 35 in Biotechnology by Clavix score.

PriceMacroSectorNewsFinancial

How rough the ride is

NBIXBiotechnology median
Betavs the overall market · lower is steadier0.340.51
Volatilityannualized8.4%14.5%
Max drawdown, past yearworst peak-to-trough fall−27.2%—
Typical daily movemedian absolute daily change1.12%—
Days beyond ±3%of the last 252 sessions30 (12%)—

How its days are spread

Daily returns over the last 252 sessions in 1% bins. Moves beyond ±6% land in the end bins.

52-week range

NBIX
142.00

The bar runs from the lowest to the highest close of the last 252 sessions; the marker is the latest close.

Drawdown from the 1-year peak

NBIX

Percent below the running high over the last 12 months. Zero is a fresh high.

Market sensitivity

NBIXBiotechnology median
Beta to the markethow much it swings with the S&P 500 · lower is safer0.340.51
Macro sensitivityrate, dollar and credit exposure bucketLowLow 53% of 36

Where it sits on the macro scale

Low 19Moderate 9High 4Very High 4

Low means rates, the dollar and credit spreads barely move it. Very High means they drive a large share of its swings. The counts are how many Biotechnology names sit in each bucket.

Where it ranks in its sector

Sector
Biotechnology35 companies ranked
NBIX
#6 of 35

Rank by Clavix score within the sector. Right is the top of the sector.

Price performance

NBIX
1 week+5.1%
1 month−1.4%
Year to date+0.5%
1 year+1.4%

Context for the rank, not itself a risk measure.

Recent coverage, scored

NBIX
Articles scoredthe most recent scored coverage, up to 3030 since 9 Aug
Average score0 most bearish, 100 most bullish56
Bullish · bearisharticles above 60 · below 4018 · 7
Directionarticles whose tone is improving vs worsening18 ↑ 7 ↓

Where the article scores land

Each bar is a 10-point band of article scores. Below 40 reads bearish, above 60 bullish.

Balance sheet, against the sector

Debt / equityTotal debt vs shareholder equity · lower is stronger
0.00sector median 0.47 · 36 names
Current ratioShort-term assets vs liabilities · higher is stronger
3.39sector median 3.73 · 36 names
FCF marginFree cash flow as a share of revenue · higher is stronger
26.2%sector median 26.4% · 24 names
Interest coverageOperating income vs interest expense · higher is stronger
3.0×sector median -0.2× · 32 names

The shaded band is the middle half of the 36 Biotechnology names Clavix covers; the tick is the sector median.

Growth

NBIX
Revenue growthyear over year+21.4%

Financial Health is shown but does not count toward the grade. Why

0–100, higher is safer. The tick on each bar is the Biotechnology median. Click a dimension for the evidence behind it. Financial Health is shown but does not count toward the grade.

Recent news

most recent scored articles · the chip is the article’s score · click to open

Neurocrine Biosciences initiated a Phase 2 study of oral NBI-1117567, also called NBI-'567, as an add-on treatment for cognitive impairment in adults with mild to moderate Alzheimer's disease. The drug activates muscarinic M1 and M4 receptors, with a preference for M1.

Source PRNewsWire Significance minor Impact product Risk improving

Read the article →

Neurocrine Biosciences presented real-world medical record evidence showing how the challenges of living with classic congenital adrenal hyperplasia (a genetic hormone disorder present from birth) shift from childhood, where growth and bone-age are tracked, through adulthood, where puberty and reproductive health become concerns.

Source prnewswire.com Significance minor Impact product Risk improving

Read the article →

Neurocrine Biosciences announced new real-world data showing how the clinical and day-to-day burden of classic congenital adrenal hyperplasia (CAH) changes from childhood through adulthood, based on decades of patient medical records. The findings will be presented at the Endocrine Nurses Society Annual Symposium on Oct. 16-17, 2026, in Phoenix.

Source PRNewsWire Significance minor Impact product Risk improving

Read the article →

Patient advocates and some experts are publicly raising safety concerns about Neurocrine Biosciences' rare disease drug Vykat XR, which is used to treat Prader-Willi syndrome (a condition that causes constant feelings of hunger). Since Vykat XR was approved 18 months ago, regulators have received case reports of seven deaths and nearly 100 hospitalizations among people taking it. Reports to regulators do not prove the drug caused these events, and many cases involved complex medical issues and multiple medications, though some experts argue the evidence is enough to show unacceptable harm.

Source statnews.com Significance moderate Impact regulatory Risk worsening

Read the article →

Patient advocates and experts are raising alarms about safety issues with Vykat XR, a Neurocrine Biosciences drug approved to treat Prader-Willi syndrome (a rare disorder causing extreme hunger). Since the drug was approved 18 months ago, seven deaths and nearly 100 hospitalizations have been linked to it, though case reports do not prove the drug caused these events.

Source statnews.com Significance moderate Impact regulatory Risk worsening

Read the article →

Nearest peers by size

Biotechnology
TickerCompanyGradeMkt capP/EBeta
ASNDAscendis Pharma A/SB+$14.62B17.250.39Compare
HALOHalozyme Therapeutics IncB$14.12B33.620.93Compare
BBIOBridgeBio Pharma IncB$13.21B—0.95Compare
EXELExelixis IncB+$15.95B18.430.44Compare
MDGLMadrigal Pharmaceuticals IncB$10.80B—-1.08Compare
INSMInsmed IncC$20.89B—0.83Compare
KRYSKrystal Biotech IncB$9.63B40.030.65Compare
TWSTTwist Bioscience CorpD+$9.39B—2.19Compare

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