TWST · Twist Bioscience Corporation
Price
Snapshot
50 fields · last close| Market Cap | $9.24B |
| P/E | — |
| Float | 65.79M |
| Beta | 2.30 |
| Volatility 30D | 124.3% |
| Exchange | NASDAQ |
| Sector | Biotechnology |
| Cap tier | Mid cap |
| Macro sensitivity | Very High |
| Clavix score | 40.4 |
| Price | 122.90 |
| Change | −13.80% |
| Prev Close | 142.58 |
| Open | 140.78 |
| Day Low | 131.32 |
| Day High | 142.98 |
| Avg Vol | 2 |
| Avg $ Vol | $336.6M |
| 52W High | 219.71 |
| 52W Low | 23.30 |
| 52W Pos | 50.7% |
| From High | −44.06% |
| From Low | +427.47% |
| Max DD 1Y | −37.05% |
| Spread | 0.10% |
| Liquidity | Normal |
| SMA 20 | −17.07% |
| SMA 50 | −19.46% |
| SMA 200 | +35.87% |
| RSI (14) | 46.4 |
| Vol 90D | 100.3% |
| Vol 1Y | 80.8% |
| 1Y Range | 23–220 |
| Daily bars | 549 |
| Perf Week | −17.80% |
| Perf Month | −14.61% |
| Perf Quarter | +30.71% |
| Perf Half Y | +139.51% |
| Perf Year | +351.63% |
| Perf YTD | +279.44% |
| Prev Day | −13.80% |
| Clavix | D |
| Debt / Eq | 0.01 |
| Curr Ratio | 3.64 |
| Int Cover | -801.0× |
| FCF Margin | — |
| Rev Growth | +20.3% |
| Profit | Unprofitable |
| Leverage | Low |
| Sector rank | 30 / 35 |
Clavix risk grade
regraded every trading dayTWST grades D, 40.4 of 100. Steadiest on News Sentiment (67), most exposed on Price Stability (14, weak). 1 of the 4 weighted dimensions sit above the Biotechnology median. Ranks 30 of 35 in Biotechnology by Clavix score.
How rough the ride is
| TWST | Biotechnology median | |
|---|---|---|
| Betavs the overall market · lower is steadier | 2.30 | 0.49 |
| 30-day realized volatilityannualized, from daily closes | 124.3% | 46.0% |
| Max drawdown, past yearworst peak-to-trough fall | −37.1% | — |
| Typical daily movemedian absolute daily change | 3.06% | — |
| Days beyond ±3%of the last 252 sessions | 129 (51%) | — |
How its days are spread
Daily returns over the last 252 sessions in 1% bins. Moves beyond ±6% land in the end bins.
52-week range
The bar runs from the lowest to the highest close of the last 252 sessions; the marker is the latest close.
Drawdown from the 1-year peak
Percent below the running high over the last 12 months. Zero is a fresh high.
Market sensitivity
| TWST | Biotechnology median | |
|---|---|---|
| Beta to the markethow much it swings with the S&P 500 · lower is safer | 2.30 | 0.49 |
| Macro sensitivityrate, dollar and credit exposure bucket | Very High | Low 54% of 35 |
Where it sits on the macro scale
Low means rates, the dollar and credit spreads barely move it. Very High means they drive a large share of its swings. The counts are how many Biotechnology names sit in each bucket.
Where it ranks in its sector
Rank by Clavix score within the sector. Right is the top of the sector.
Price performance
| TWST | |
|---|---|
| 1 week | −17.8% |
| 1 month | −14.6% |
| Year to date | +279.4% |
| 1 year | +351.6% |
Context for the rank, not itself a risk measure.
Recent coverage, scored
| TWST | |
|---|---|
| Articles scoredthe most recent scored coverage, up to 30 | 30 since 26 Jul |
| Average score0 most bearish, 100 most bullish | 59 |
| Bullish · bearisharticles above 60 · below 40 | 18 · 9 |
| Directionarticles whose tone is improving vs worsening | 18 ↑ 9 ↓ |
Where the article scores land
Each bar is a 10-point band of article scores. Below 40 reads bearish, above 60 bullish.
Balance sheet, against the sector
The shaded band is the middle half of the 35 Biotechnology names Clavix covers; the tick is the sector median.
Growth
| TWST | |
|---|---|
| Revenue growthyear over year | +20.3% |
Financial Health is shown but does not count toward the grade. Why
0–100, higher is safer. The tick on each bar is the Biotechnology median. Click a dimension for the evidence behind it. Financial Health is shown but does not count toward the grade.
Recent news
most recent scored articles · the chip is the article’s score · click to openPolen Capital said Twist Bioscience was a leading relative contributor to its Small-Mid Growth Strategy in Q3 2026, supported by strong operating results and improved guidance; the headline also cites record revenue and AI-driven demand. The portfolio fell 12.52% after fees during the quarter but remained ahead year to date, gaining 8.14% versus 7.28% for the Russell 2500 Growth Index.
Industry analysis has named Twist Bioscience as a key company in the biofoundry-as-a-service market, which is forecast to grow to roughly $4.38 billion by 2030 as biotech firms and research labs adopt AI-enabled, automated biological engineering platforms.
The article says Moderna’s stock surged after results from its personalized cancer vaccine, while Twist Bioscience’s synthetic DNA is seeing strong demand. The supplied text provides no figures or further details, so the substance is insufficient for a fuller assessment.
Twist Bioscience CEO Emily Leproust sold 5,203 shares of company stock on September 24th at an average price of $177.38 per share, for total proceeds of $922,908.14. After the sale, she directly owns 613,699 shares.
Twist Bioscience CEO Emily Leproust sold 1,687 shares on September 21st at an average price of $165.49, totaling about $279,182. After the sale she still holds 618,902 shares in the company.
Nearest peers by size
Biotechnology| Ticker | Company | Grade | Mkt cap | P/E | Beta | |
|---|---|---|---|---|---|---|
| MDGL | Madrigal Pharmaceuticals, Inc. | B | $9.25B | — | -1.03 | Compare |
| KRYS | Krystal Biotech, Inc. | B | $9.21B | 38.12 | 0.71 | Compare |
| PTGX | Protagonist Therapeutics, Inc. | B | $9.28B | 110.85 | 1.21 | Compare |
| CAI | Caris Life Sciences, Inc. | C | $9.39B | 88.30 | 0.41 | Compare |
| TGTX | TG Therapeutics, Inc. | B- | $9.43B | 21.06 | 1.77 | Compare |
| CYTK | Cytokinetics, Incorporated | B+ | $8.84B | — | 0.40 | Compare |
| ARWR | Arrowhead Pharmaceuticals, Inc. | C+ | $8.71B | — | 1.39 | Compare |
| IONS | Ionis Pharmaceuticals, Inc. | B- | $6.67B | — | 0.36 | Compare |
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